Endocrine Abstracts

Background: Adrenal insufficiency (AI) poses a significant health burden on patients, their families, and the healthcare system. Cost of illness for this patient population is four times higher than the general population. Hospital admissions due to adrenal crisis (AC) form a considerable proportion of this cost. Almost 1 in 200 patients die from AC. One in 12 patients with AI are hospitalised at least once a year following an acute AC episode if not treated promptly with pare...

Background: Adrenal Insufficiency (AI) is an inadequate production of cortisol hormone from the adrenal glands. The most common form is secondary AI (suppression of the hypothalamic-pituitary-adrenal axis), with a prevalence of approximately 300 cases per million. Patients with AI require lifelong corticosteroid replacement, which poses a risk of a life-threatening adrenal crisis (AC) event. AC presents with low blood pressure, hypoglycaemia and even loss of consciousness. Thi...